PReS-FINAL-2252: Descriptive analysis of pediatric autoimmune neuropsychiatric disorder associated with streptococcus infection (PANDAS) in a cohort of 65 Italian patients
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چکیده
Methods Descriptive analysis of a cohort of Italian patients with PANDAS.Between may 2009 may 2013 we observed 65 pts (50 M, 15 F, mean age: 100.8 ± 32,9 months) with OCD and/or tics starting before puberty, associated with a previous GAS infection. Demographic and familiar data, routine and specific laboratory data: thyroid function, autoimmunity tests (ANA, anti-dsDNA, antiENA, anti-cardiolipin, and anti-tissue transglutaminase antibodies) were collected. 55/65 underwent brain MRI, all EEG, echocardiography and neuropsychiatric evaluation.
منابع مشابه
From pandas to pans: a nosographic entity in evolution throughout a descriptive analysis of a cohort of 103 italian children and adolescents
Introduction The acronym PANDAS reveals a pediatric autoimmune neuropsychiatric disorder associated with Streptococcus pyogenes infection. This disorder is defined by: (a) the presence of obsessive-compulsive disorder (OCD) or tics; (b) abrupt onset and remitting/relapsing course; (c) prepuberal onset of all symptoms; (d) temporal association with a group A b-hemolytic S. pyogenes infection; (e...
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